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LBP is the largest cause of morbidity worldwide, yet there remains controversy as to the specific cause leading to poor treatment options and prognosis. This project utilises intervertebral disc degeneration (LDD) leading to low back pain (LBP) as a relevant application for the integration of data and computational simulations in translational medicine, to enable rational interpretations of the complexity of the interactions that eventually lead to symptoms. Sylki ja sen merkitys suun terveyden kannaltaĭisc4All training network to advance integrated computational simulations in translational medicine applied to intervertebral disc degeneration The second aim is to study the associations of certain general diseases, such as asthma and sleep apnea, with dentofacial morphology.Įating and physical activity behaviors in women with PCOS: associations with body image, temperament, and psychological wellbeing The main objective of this study is to investigate the variations and covariations of occlusion, dental arch morphology and facial morphology in the Northern Finland Birth Cohorts (NFBC) 19. The dental arch form has been suggested to be associated with dental malocclusions, craniofacial deviations and mouth breathing. Dental arches and occlusion develop under the influence of function, such as breathing and chewing, and mild changes occur throughout life. The evaluation of occlusion, dental arches and facial characteristics are important part of the orthodontic treatment planning. Variation and covariation of occlusion, dental arch shape and facial shape The study results will guide healthcare professionals to pay attention to the important health and life quality issues when facing women with early menopause. In this study, we investigate several important aspects of early-onset menopausal transition. Up to 12% of women face menopause by the age of 45, but only a few studies have investigated health outcomes in them. It is known that menopause before the age of 40, concerning about 1-2% of women, exposes women to adverse health outcomes. We aim to investigate comprehensively the health and well-being of women facing menopause by their mid-40s. Mental health, sexual well-being, autoimmune disorders, lifestyle habits, sleep disorders, telomere length, cognition, work disability and cardiovascular morbidity in relation to menopausal status in the mid-40s. Suvi-Päivikki Sinikumpu, Kaisa Tasanen-Määttä ( disordersĪrctic Biobank – University of Oulu, NFBC project centerĪrctic.biobank(at)oulu.fi NFBCprojectcenter(at)oulu.fi Riitta Kaarteenaho, Johanna Salonen ( diseases Juha Veijola, Jouko Miettunen, Erika Jääskeläinen ( ADHD and Exlusion Markku Timonen ( Schizophrenia and other psychoses
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Raija Korpelainen ( Timo Jämsä ( Kajantie( Anxiety and depression Tuula Salo ( Laitakari, Samuli Hannula ( activity and nutrition George Sandor ( Diseases of mucous membrane Marja-Liisa Laitala ( Facial pain and TMD Jaro Karppinen, Juha Auvinen ( Remes, Kari Majamaa ( health Timo Hautala ( Ala-Korpela ( Ala-Korpela, Johannes Kettunen ( and inflammation Ville Saarela ( Liinamaa ( Ronkainen, Karl-Heinz Herzig ( Piltonen, Laure Morin-Papunen ( diseases and immunology Sylvain Sebert ( Marjo-Riitta Järvelin (m.jarvelin(at)imperial.ac.uk) Juha Pekkanen ( Tulppo ( Kari Kaikkonen ( Auvinen, Sirkka Keinänen-Kiukaanniemi ( growth and development